Nasal DNA methylation profiling of asthma and rhinitis
نویسندگان
چکیده
منابع مشابه
Stronger nasal responsiveness to cold air in individuals with rhinitis and asthma, compared with rhinitis alone.
BACKGROUND We have previously proposed that, compared with rhinitis alone, the constellation of upper and lower airway allergic disease is a manifestation of a more severe form of a syndrome affecting the entire airway. If this is correct, not only the lower, but also the upper airways of patients with asthma and rhinitis should demonstrate more abnormalities compared with patients with rhiniti...
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BACKGROUND Treatment response to systemic corticosteroid in asthmatic children is heterogeneous and may be mediated by epigenetic mechanism(s). We aim to identify DNA methylation (DNAm) changes responsive to steroid, and DNAm biomarkers that distinguish treatment response. MATERIALS AND METHODS We followed 33 children (ages 5-18) presenting to the Emergency Department (ED) for asthma exacerba...
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Sexual intercourse as a trigger factor for attacks of asthma and/or rhinitis and the morbidity caused thereof is not well recognized. We present four patients (three males and one female) with postcoital asthma and/or rhinitis. Acute severe asthma subsequent to sexual intercourse in one male patient had resulted in several emergency department visits and hospitalization on one occasion. Anxiety...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2020
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2019.12.911